
产品货号:
Z15152
中文名称:
E2F6抗体
英文名称:
Anti-E2F6 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-E2F6 Antibody |
指标别名 | E2F transcription factor 6;E2F-6;E2F6;EMA |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,ELISA |
基因名称 | E2F6 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human E2F-6 |
计算分子量 | 32KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | E2F6(E2F transcription factor 6) also known as E2F-6.Northern blot analysis revealed that E2F6 is expressed as 2 mRNAs,2.5 and 3.5kb,in all human tissues and cell lines tested.The predicted human and mouse E2F6 protein sequences are 92% identical.The DNA-binding and dimerization domains of E2F6 are highly related to those of other E2F family members,but this protein lacks the sequences necessary for either transcriptional activation or binding to RB1,p107,or p130.E2F6°Can act to repress the transcription of E2F-responsive genes by countering the activity of other E2F complexes.E2F6°Contributes to gene silencing in a manner independent of retinoblastoma protein family members.E2F6 is found in a multimeric protein complex that contains MGA and MAX,and thus the complex can bind not only to the E2F binding site but also to MYC- and Brachyury- binding sites.The E2F6°Complex preferentially occupies target promoters in G0 cells rather than in G1 cells. |
Uniprot ID | O75461 |
基因名全称 | Transcription factor E2F6 |
蛋白名全称 | Transcription factor E2F6 |
推荐稀释比 | WB 1:500~1:2000 IHC 1:100~1:300 ELISA 1:20000 |
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